This figure shows the heme group and the portion of the hemoglobin protein that is directly attached to the heme. As shown in the figure, the conformational change in the heme group upon oxygenation causes the entire hemoglobin protein to change its conformation as well. Please click on the pink button below to view a QuickTime movie showing how the amino acid residues near the heme group in hemoglobin shift as the heme group converts between the nonplanar (domed) and the planar conformation by binding and releasing a molecule of O2.


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