Traditional STR analysis can be used to create a DNA profile from weakened evidence but materials like blood or semen may be too destroyed for PCR testing to generate an accurate profile. However, the hair shaft can be analyzed using mtDNA and can then play an important role in solving the case. Mitochondrial DNA is passed down to all of the offspring from only the mother, so all maternal relatives have the same mitochondrial DNA. Among other things this allows unidentifiable remains to be identified using the mtDNA of any maternal relative.


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