The target population for this study was patients with high-risk adolescent idiopathic scoliosis who met current indications for brace treatment: an age of 10 to 15 years, skeletal immaturity (defined as a Risser grade [a measure of the amount of ossification and eventual fusion of the iliac apophysis, on a scale of 0 to 5, with higher grades indicating greater skeletal maturity] of 0, 1, or 2), and a Cobb angle for the largest curve of 20 to 40 degrees. To be eligible, patients could not have received previous treatment for adolescent idiopathic scoliosis (Table S2 in the ). Eligibility was determined by the local investigators. Standard information about the trial was presented to eligible patients by means of an online education module.


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